I experience something that looks like this problem.
BOT registred via on-prem wifi, OK.
Then moves to MRA, IM&P and VM works,but CUCM registration fails (SIP/2.0 488 Not Acceptable Media)
Resetting the device in CUCM seems to allow registration again.
BOT is not in secure mode when on-prem.
CUCM version: 12.0.1.21900-7
BOT version: 12.1.0.266498
fortvald