You can use HyperFlex with CCE. In fact, I have a project going on right now where the customers current production environment is all B series and their new environment is all HyperFlex.
The HyperFlex series is on the Virtualization page for UCCE under BE7000H Large TRCs, you'll see it as the HX220C M5SX. The project I'm working has HX240C, which is a bit larger. And although the HX240C is considered spec-based, it is fully supported and will pass A2Q.
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