The short answer is no, there is no feature to do that. Once messages land in the workqueue, they are scanned FIFO (First in-First Out).
If your appliance actually has 5,000 messages in the workqueue, it is wildly overloaded and is probably either in resource conservation throttling or very close to it. Once you hit resource conservation the ESA will start to throttle acceptance for all recipients on a global basis so there is no way to specify priority for one specific email address.
In addition, this would cause the ESA to waste time and cpu scanning messages in the workqueue twice. It would have to immediately check new messages for a match and if no match, go back to working on clearing the workqueue. When you have an appliance already overtaxed, any extra work can be a big issue.
Sounds like you might need a beeger bawx. :)