i have this alart ( The last synchronization attempt on 2015-Nov-15 00:30:34 failed because the instance was unreachable. The last successful synchronization with this instance was 2015-Nov-08 00:31:04.)
in (Cisco PrimeLicense Manager) whin i try to synchronization with the instance this alart shows up (Test Connection Failed.The connection timed out while trying to reach the Product Instance. Verify that it is online and the provided hostname/IP address is correct.)
Did you try to restart the instance PLM is reporting not able to communicate with. If not, then please try restarting the respective instance/server what ever it is Call Manager or Unity Connection.
Just check if this bug gives some direction for resolution even it is for UCXN
In addition to what Chris has said, do check utils dbreplication runtimestate for dbreplication between PUB and SUB.
Are u able to enter with same credentials through putty in Publisher?
Sounds like the server may be down, and you may be running on the failover server. You need to investigate if it is indeed down or perhaps has network connectivity problems.