I think I already know the answer to this question but here goes. Can I in the same fiber run mix OM1(62.5 micron) and OM4(50 micron) fiber? I have an existing run with OM1 and would like to not have to replace it.
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The below link provides a good overview of the implications of mixing fiber sizes (62.5um and 50um).
If you have looked at the FOA technical analysis of "Power Penalty For Mixing 50/125 And 62.5/125 Fibers In One Link", you might find it is feasible to mix them in a cable run, just remember to use color-coded cables. Even if you're running below GBE now and having a long OM1 cable, I still suggest you to replace it. Because you'll have to replace it soon or later. And if you're running at GBE, there's no doubt to replace OM1 with 50um fiber. It is not worth to tolerate the large amount of losses for the long term.