Adding IKEv2 to the list of tunneling protocols wouldn't have an impact on the other connection profile settings that also reference the default policy you are just allowing another tunneling protocol along with the ones you already have enabled.
Although personally I would create a new group policy for the site to site connections just to keep things more organized but if you want to use the default policy that is ok too.
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This document is to provide any changes made to endpoint OS that impacts BYOD flow for end users.
Prior to troubleshooting endpoint issues, please follow these steps first:
Update OS finger printing DB on ISE: This is done by going to Adm...
"Cisco is aware of the recent Fxmsp hacking claims and confirmed we are not among the vendors named. At this time, we are not aware of additional information that links Cisco products to source code or assets involved in this issue, including Cisco AMP an...