ISR 4321 DUAL NIM-4MFT-T1/E1 Support

[FabioYamaia]

It is known that ISR 4321 does NOT supports NIM-8MFT-T1/E1, but does it allows combined use like:

NIM-4MFT-T1/E1 + NIM-1MFT-T1/E1 modules

or

NIM-4MFT-T1/E1 + NIM-4MFT-T1/E1 modules

If yes, do I need to use one PVDM-4 for each card?

Thanks in advance.