in my opinion it depends on two things; 1) the number of vlans in the environment and 2) the comfort level with mst. if the number of vlans is small then PVRSTP is fine. MST is more (slightly) more difficult to configure and maintain, so if you are not comfortable with MST then stick with PVRSTP. My two cents.
Thanks Bill, Potentially we'll have up to 85 VLAN's, in total.
Vlan ranges will fall between.
Vlan range 1-3709.
What would the configuration look like?.
I would stick with PVST with this number of vlans. Configuration would be the same as on a 6500, the only differences would be the spanning tree priority would be the same on both Nexus vPC peer switches. I would also recommend setting "spanning-tree pathcost method long" on all the nexus switches in the environment.