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Nexus 7K 5K VPC design issue

Hi Experts:

 

Will this topology cause performance issue??

We find out tcp out of order retransmission for some client(problemed client change ip address can be fine)

For Nexus 7K and Nexus 5K didn't run double-sited vpc will be the reason?? why??

 

thanks!!

 

 

 

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