Yes you can, but not as you drawn.
If you want vPC in non VSS environment , you should have each 6k connected to each 5k.
- faster failover
- non blocking ports -comparing with same setup , but running STP
In order to use vPC you should have the 5k interconnected.
Thanks for your reply. yes our 65k are connected to each 5K and both 5k are connected togehter....let me try this....i hope it will work...hv u tested it ?/
I do not have exactly the same setup , mainly because of the VSS. I do use vPC for the server side. So you can consider that I have a server in place of your 6k.
Here is a one of the most optimel topologies described here in the forum:
You can parse the forum sor similar topics - it's quite popular question.
Also here are some videos on n5k and cat6k
and ofcourse vpc config video