I am going to design one network and currently there is 4506-e switch as Core and it contains these cards-
WS-X4624-SFP-E so Please let me know whether shall i replace this whole device or card only.
Please suggest as 4506-e might not be EOL ,I am not sure please please suggest.
On the basis that a new 24-port 1GE SFP card for a 4506 is about the same list price as a 48-port 1/10/25G SFP+ switch in the 9500 series, I would opt for the latter. Even the ageing 32-port 4500X would seem a better bet than the 4506 line card. Both of these options have massively increased backplane capability compared to the chassis and give future capability to move to 10GE. In addition, they save you 9RU in your rack.
Going to 12x10GE cards would be even more expensive.
Hope this helps,