There is only one publisher per cluster and the database is replicated to the subscribers.
How big is you cluster? How many nodes, how many phones.
Our environment consists of 4 UCS boxes in two geographic locations.
Pubs (TFTP, CUC, CUCM, IMP) are in our Data Center 1 and are split between two chassis, CUCM subs 1 and 2 are also split between the servers.
CUCM Subs 3 and 4 are split between 2 chassis in Data Center 2 along with TFTP, CUC, IMP subs.
Hope that helps.
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