You cannot change absolutely nothing via any GUI if the PUB is down, only the pub has a read/write database. If the pub is down, all the SUBs go to read-only mode and only UFF can be made to the DB (and only via the phone). Whatever you need to change, will have to wait until the PUB is back up
If all the servers are up, the change is done in the PUBs DB an then replicated to all other servers.
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