OK awesome.  Thanks for the clarifications.  So with the AnyConnect, the solution is possible?AnyConnect VPN Client user would be IPv6 only (but with the IPv4 stack installed on the computer)Cisco ASA public facing interface would be IPv4 and IPv6 (D...

Thanks Harold, I've been doing some more digging and found some stuff that might contradict your statement.  Granted, it's been a while since I've had to work with this client VPN stuff, maybe I have the terminology wrong (VPN Client vs AnyConnect Cl...

Same/similar question but the case is instead of Site to Site VPN, it would be using the Cisco VPN Client.  The host on the left side is connected to an IPv6-only network.  They need to communicate with IPv4 devices across the Internet (behind a Cisc...