I am having the same issue. Brand new ISE boxes.  Two boxes with each one running all services (PSN,PAN,MNT) in primary and secondary. If Primary box unreachable, authentication will still work, but posture fails with server issues error. TAC open bu...

Upgraded our FMC and one 2110 FTD to 6.4  WCCP no longer works.  Cisco TAC looked at it already and no fix.  Had to re-image device to get back on older code.  Others having issues as well?

Has anyone upgraded to Firepower 6.3 yet?  If so, what version did you upgrade from?  Any issues?     We are running 6.2.3.6.