Well that was an interesting journey. TAC ran some diagnostics and found the following DB error:
<195>Apr 28 12:16:45 localhost j9: ERROR dbclient database mgmt **** ERROR: column "smtpserver" does not exist
His solution was to backup, reinstall and restore CUE. I ended up comparing the CUE running config to a similar setup and found an incorrect gateway address under the ccn subsystem sip: ccn subsystem sip gateway address "10.1.1.1" dtmf-relay sip-notify end subsystem I changed this, saved and rebooted and messages began to be delivered. Yaay, no need to reinstall CUE!
Thanks again for the assist!