For a few years, with multiple client versions, we've seen an issue where sometimes AnyConnect will connect just fine, but not receive data for a few minutes after the initial connection burst. The connection stays up just fine, and I can see in the Statistics tab that it's continuing to send small amounts of data, but the "received" doesn't budge for several minutes. Then it just starts sending/receiving data normally. Usually you can just disconnect and reconnect and things will work right away. In my last test I had to connect/disconnect probably 20 times to get it to experience the issue, so it's very intermittent.
Has anyone experienced anything similar? If so, what did you need to do to troubleshoot / tweak?