HI Ramu,
Hope you are doing fine,
I checked the configuation that you have attached and it looks fine to me
Could you please configure following captures on the ASA
access-list test per ip host host
access-list test per ip host host
access-list test per ip host host
access-list test per ip host host
capture vpn access-list test interface inside packet-length 1522
capture drop type asp-drop all
After configuring these captures telnet on port 25 and 21 to the server.
Issue show cap vpn and show cap drop to get the output of the captures.
Also check the logg messages on the ASA while you telnet
Make sure that there is no Policy based routing configured on the router for SMTP and FTP
Regards
Ashish