Hi all,
I have upgraded our S100V to AsyncOS Version 10.5.2-042 and started to fail. For some reason after the upgrade, all the outbound connections from the proxy to any webserver go to destination port 8888 instead of 80/443.
After having a look, i realized that port 8888 is the port configured to host the PAC file. I disabled PAC file hosting feature and then started to work fine.
This is a big bug and haven't found any information about it. Now rolling back to previous firmware version.