If you are simply going to authenticate dial-in users, based on their username/password, via Radius, then this will be possible using standard IETF attributes that both Cisco IOS as well as Microsoft's IAS support without additional configuration.If you want to use any vendor-specific functionality, then you can go for VSAs.
Examples for vendor-specific functionality where extra configuration on IAS is needed would be per-user attributes such as per-user static routes or per-user access lists, as these are implemented using Cisco VSA's. Similary, Microsoft VSA's need to be used if Microsoft proprietary functions, such as MPPE, are to be used. This document might be of use for you:
http://www.cisco.com/univercd/cc/td/doc/product/software/ios120/12cgcr/secur_c/scprt6/scradatb.htm#8767