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If you can provide us with the "system support trace" output of where the traffic gets blocked by stream we should be able to provide some better guidelines around this.
This can happen when an access control rule has not finished evaluating a connection and at that point the connection just breaks our stops outside the firewall. At that point the rule was still pending and it logged the latest state it was evaluatin...
See our details on the Dynamic Attributes Connector here.
There is also a table with all the connectors and respective versions for them.
https://secure.cisco.com/secure-firewall/docs/cisco-secure-dynamic-attribute-connector
For the Applications base...
Just curious,
Is there a reason you chose to use an external script vs what we currently have now with all our Office 365 applications or even the "Dynamic Attributes Connector" with the Dynamic Objects that processes and updates all those IP's dynam...
In general, try to use the "configure manager add IP passkey nat" values for such environments.
Make sure that both vFTD/vFMC are able to communicate to each other either by ssh into them or ping.
Sometimes small networking configuration issues in A...