hello,
sure it's pretty easily possible
//to allow traffic using acl)
access-list vendorone permit tcp host abcd host xxxx eq 21
access-list vendortwo permit tcp host wxyz host yyyy eq 21
//to nat
nat (inside) 10 access-list vendorone
nat (inside) 20 access-list vendortwo
//to specific which ip to nat
global (outside) 10 192.168.1.1
global (outside) 20 172.20.1.1
or you can directly nat
nat (inside) 10 >ip you want to nat<
global (outside) 10 >ip you want to be natted to<
HTH, PRI