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you can check also this doc:https://documentation.meraki.com/General_Administration/Cross-Platform_Content/Behavior_during_Connection_Loss_to_Cisco_Meraki_Cloud
1) you might hit following defect. please check this. https://bst.cloudapps.cisco.com/bugsearch/bug/CSCvn516252) also check following connections through ESA's CLI: telnet update-manifests.sco.cisco.com 443 telnet downloads.ironport.com 80 telnet...
oh. I see this is Cloud-based Host. seems you don't have permission for 'Alerts' tab. However, you should receive alert notifications via email.can you please share URL of SMA ?If you can confirm that messages quarantined are normal in terms of size ...