almost after 45 minutes, ISE also fully loaded   ...  it's much slow to load than week ago   ..But i can see DNAC and ISE both as Up now .. !Thanks ! 

Thanks @bigevilbeard I checked today .. DNAC loaded this time   . But ISE still not loading .."Application server is initializing.You will be automatically redirected to the login page."  when i do a ssh for ISE it gives Auth error with correct passw...