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You can get the Cisco VPN 5.x fat client to work even with build 1511. I use it daily.
Instructions here. http://itthatshouldjustwork.blogspot.com/2015/07/cisco-64-bit-vpn-client-on-windows-10.html
I would recommend you fully remove the DNE software and the client. Follow the instructions posted here and you will be good to go. http://itthatshouldjustwork.blogspot.com/2015/07/cisco-64-bit-vpn-client-on-windows-10.html?m=1
