Hey Andril,
You can see URL interaction on the Cisco ESA/CES when you enable URL rewrites to the Cisco Secure Proxy - and any rewritten URL will show click interaction.
You will also need to enable the URL interaction logging on the GUI > Security Services > Outbreak filters.
Now for Click-time protection to the level in which I think you're looking for - from my knowledge; the full click-time protection is only done for URLs rewritten by the outbreak filters.
The Content filter URL rewrites would allow for click interaction tracking; but I believe it's a bit more limited in terms of click-time protection as opposed to the Outbreak filters URL rewrites you can configure when an outbreak filter rule gets triggered.
I hope this answers your query.
Thanks,
Mathew