How To: Cisco & F5 Deployment Guide: ISE Load Balancing Using BIG-IP > About This Document says,
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Many features may exist that could benefit your deployment, but if they are not part of the tested solution they may not be included in this document. Other configurations are possible and may be working successfully in your specific deployment, but may not be covered in this guide due to insufficient testing or confidence for a stable deployment. ...
The Citrix NetScaler configuration was contributed by a Cisco engineer in Cisco services teams.
Regarding one-arm, see Craig's response in ISE behind load balancer