Yes this is possible.
It will require 2 InLine Interface Pairs on the sensor and both pairs should be added into the same Virtual Sensor.
The 4260 will not be aware that etherchannels are used on both sides, and does not need to be aware.
This may,however, require manual enablement of the etherchannels.
Also keep in mind that the performance in this setup will be limited to what the IPS-4260 is able to perform with that traffic.
If the IPS is only able to monitor 1 Gbps (which is its rating for Transactional traffic tests), then having the 2 InLine Interface Pairs will not give them any more performance than a single pair would.
If the IPS is able to monitor more than 1Gbps of their traffic (it is rated at 2Gbps for Media Rich tests), then the additional pair will allow the sensor to get to the above 1 Gbps monitoring.
If the 4260 is not able to keep with the traffic, then an upgrade to a 4270 using the same deployment setup may be necessary.
NOTE: This also assumes that only the left or right path are actively passing traffic at any one time. If both paths are passing traffic, then asymmetric traffic patterns can result. if asymmetric traffic is seen, then another deployment should be considered, or specifial configuration be placed on the sensors.
NOTE: This setup only works when a single sensor is used within the etherchannel. (1 sensor on each etherchannel, 2 sensors in your diagram because you have 2 etherchannels).
You can not place 2 sensors in the same etherchannel (would mean 4 sensors in your diagram).
This is because the balancing being done from the lower switch can not be guaranteed to match that being done from the top switch. A mismatch in balancing could lead to asymmetric patterns.
With a single sensor, the same virtual sensor sees all traffic regardless of which interface the packet comes in on, so a single sensor is fine. But with 2 sensors, the client traffic might get sent to a different sensor than the server traffic.
