Greetings!
In this week's What's new in CDO it was announced that the new Cisco Defense Orchestrator (CDO) public API has moved from beta to general availability! You can find the API docs here. There is the REST API, a postman collection, and a python SDK available now via pipi with
pip install cdo-sdk-python
This API is fully supported and don't forget that your first stop for help should be over in Cisco DevNet land!