Signature 3327-6 will detect this Metasploit module, however it is disabled by default.
Description:
Subsig 6 fires when a potential buffer overflow attempt against a Windows DCOM RPC service is detected. This may indicate a system compromise.
This is a 5.x only signature.
However, as noted in the benign triggers section for signature 3327-6:
False positives have been reported with this signature. To help identify malicious traffic it is recommended that you look for alerts from one of the 3328-* signatures from the same source.
So one should only enable this signature for a specific cause.
We are currently investigating improving the fidelity of 3327-6 or possibly creating new protection for this module.
If you have already enabled 3327-6 and this is not firing, please email me the pcap at ips-signature-team@cisco.com and we will take a look.
I hope that helps, and please let us know if this does not answer your question.
Thanks
Al
Cisco IDS/IPS Signature Development Team