Please repost this question to Network Security thread.
(https://community.cisco.com/t5/network-security/bd-p/discussions-network-security)
Firepower uses AMP engine so if AMP itself supports Yara signature, maybe Firepower can have the same function. As far as I research AMP function, it has no function to implement Yara. AMP uses SHA-256, MD5 hash and ClamAV signature to detect malware. We can't convert from Yara to ClamAV signature(https://www.clamav.net/documents/using-yara-rules-in-clamav). So I think it's a quite low probability to have it in AMP and Firepower but not sure. So please post your question to Network Security thread.
