Anyconnect has 2 connection methods default is SSLVPN based-- no NAT-Traversal impact IPSec based (at present ikev2 is only supported)-- NAT-T preforms 2 things 1.Detects if both ends support NAT-T2.Detects NAT devices along the transmission path (NA...
Below Cisco AnyConnect Ordering Guide would be able to give you all related information related to posted queryhttps://www.cisco.com/c/dam/en/us/products/collateral/security/anyconnect-og.pdf