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I have followed the steps in the linked article What is the least-privileged Duo Authentication Proxy Windows service account configuration to setup a Group Managed Service Account (gMSA). I have used Group Policy to configure 1) the security on the...
Its not awesome; but you may be able to leverage the Duo Admin API to make an API to sync a single user (repeat as necessary for each user), adding that step to the annual disabling/enabling process shouldn’t be too bad.
Duo Security...