Yep, exactly: want to use OpenDNS with my dual-stack ISP. Until Amplifi supports dual-stack DNS prefs will continue using it in bridge mode, with Mikrotik external router.
AmplifiHD as a router can not configure specific IPv6 DNS resolvers; only IPv4.
I get this is not likely the case here.
But if your home ISP is dual-stack as mine is, and provides DNS resolvers, configuring OpenDNS resolvers (208.67.220.220, 208.67.2...