single node DNAC vs a three node cluster DNAC =
Single means you know by now - there is no redundancy and all in 1 Box, if that is failed, you do not have redundancy
DNAC 3 node cluster give more high availability and auto-recover ( also patch management is easy if you have cluster)
There is another deployment also there called DR - this is 1+1 +Witness (this request 2 DNAC and 1 Witness VM to Monitor DR)
more information can be find here :
https://www.cisco.com/c/en/us/td/docs/cloud-systems-management/network-automation-and-management/dna-center/2-3-4/ha_guide/b_cisco_dna_center_ha_guide_2_3_4.html
good video to start with :
https://www.youtube.com/watch?v=QOCQwR8iq3g