Hi,
I do not think this would change CPU usage by a large extent unless you have being seeing delays in DNS responses from the configured DNS servers.
I would recommend starting with command "status detail" to check what is currently utilizing CPU and "displayalerts" to see if there were any recent errors.
If you use URL filtering ensure the configuration is updated as per recommendation in the below field notice.
http://www.cisco.com/c/en/us/support/docs/field-notices/641/fn64111.html
Also below article is helpful in understanding CPU load.
https://www.cisco.com/c/en/us/support/docs/security/email-security-appliance/200468-High-CPU-utilization-after-upgrading-ESA.html
Thanks
Libin Varghese