Hi Rian,
I think this error/alarm can be seen when we have "ISE > Administration > System > Settings > Client Provisioning" configured for automatic update or Downloading Client Provisioning Resources Automatically.
It could be an network flip or internet issue.
If we have configured proxy settings Administration > System > Settings > Proxy then check if proxy server is working fine.
Make sure there is no firewall that could create issues while connecting to URL.
Cannot Download Remote Client Provisioning Resources
http://www.cisco.com/en/US/docs/security/ise/1.1/user_guide/ise_troubleshooting.html#wpxref65566
Jatin Katyal
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~Jatin