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According to the latest ISE ordering guide https://www.cisco.com/c/dam/en/us/products/collateral/security/identity-services-engine/guide_c07-656177.pdf, Plus license is not required if user and endpoint contextual attribute is exchanged -
"User and endpoint contextual attribute (w ho, w hat, w here, w hen, etc.) data exchange betw een Cisco ISE and thirdparty system through pxGrid"
Does the pxgrid connection between ISE and DNAC fall into this scenario?