hi yes you can do this.
assume you public ip address is 1.2.3.4 and you wanted to nat into your inside network. so for your internal user this address show as your internal ip address (let say your internal ip address subnet is 192.168.0/24)
object network Public-IN
host 1.2.3.4
nat (outside,in) static 192.168.1.20
!
access-list OUT-IN extended permit tcp any host 192.168.1.20 eq 80
access-group OUT-IN in interface outside
!
now added this object in your site-to-site vpn
!
please do not forget to rate.