Since the 4215 will have 5 monitoring interfaces and 1 command interface, you have a lot of flexability. The device can process up to 80Mbps whether using 1 or 5 interfaces - so keep that in mind.
Placing monitoring interfaces on the outside of the firewall can lead to a tremendous number of events, some or a lot of which may be false positives, unless you are running FW Feature Set on the 7200s. The Pix pair will filter a good bit of the traffic out, so it may make sense to put the interfaces on the 2 dmzs and perhaps one on the inside. Just keep in mind the 80Mbps total can be passing to the 4215. Everything after that will not be review for matches.
Hope this helps,
peter