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Impact of replacing ISE in SDA

We are running ISE1 standalone.
We are currently rebooting ISE1 due to an issue.
We have ISE2 ready, which is a clone of ISE1 (UCS is different).

I will disconnect the uplink of ISE1 connected to FUSION and connect the ISE2 cable.
Once ISE1 has finished rebooting, we will reconnect ISE1's uplink.

We will plan for a generous downtime of at least 1 hour to perform this operation.
Is this likely to cause any critical issues with the SDA topology?

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interesting approach... anyway, expect hitting issues if u have also DNAC-ISE PxGrid integration

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