You can take advantage of Custom URL External Feeds feature only available in WSA 10.x onwards for Skype and Office 365, as the external feed will have the exact IPs/hosts and will be updated every configured interval, Office 365 also includes the Sk...
If you are using Cisco Cloud Web Security(CWS) , you can follow the steps below to block the magic pattern iframe content.
If they would like to block the above content, they can block it by creating and AND filter Policy in scancenter. STEP-1- ...