The same issue with ISE 2.7 patch 5.  Had to roll back to patch 4 per TAC recommendation.

Hello,I have pair of ASAs in Active/Standby HA mode. ASAs have VPN tunnel going out to the data center where ISE (TACACS) servers are. I can use TACACS for the Active unit, but it seems like Standby unit can't get to ISE at all, it just times out. Si...

I would like to have single VPN URL for the whole company that has multiple office locations.  But at the same time, every location has its own ASA 5516x that can be used for users to connect.  How do I make all users connect to the single URL (possi...