This is a L4 vserver, so the CSM will just forward the SYN to the servers [no spoofing].
So, if the server does not respond to the SYN, as we can see in the trace, this should be investigated on the server side.
I believe the CSM sends a RESET because the seq# of the last SYN does not match the previous 2 packets.
But the main issue, is why the server are not responding to SYN ?
You could try to capture a port-channel trace so we can see at the same time traffic from client to CSM and traffic from CSM to server.
Gilles.