Yes, you have to.
Ensure that you configure the switchport connected to the WLC as a trunk:
switchport trunk encapsulation dot1q
switchport mode trunk
Also ensure that the VLANs used have the ip helper address pointing to the DHCP Server:
ip address 10.1.50.1 255.255.255.0
ip helper-address 10.1.100.10
Whichever ACLs you reference on your ISE must exist on your WLC:
These are the first steps to proper redirection.
Be sure to check the Admin Guide for further guidance:
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