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11-19-2019 12:52 PM
I am trying to create PXGrid certificates with Cisco ISE and I am getting an error.
Certificate generation failed: Not able to build the ISE CA chain to the root. Chain size: 2: INTERNAL_SERVER_ERROR
Can someone help me with this?
Solved! Go to Solution.
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11-20-2019 01:50 AM
Hi @Richard Lucht ,
Can you please try to rebuild the internal CA on the ISE and see if this resolves the issue?
Regenerate Internal CA of the ISE: Administration > System > Certificates > Certificate Signing Request > Generate CSR > ISE Root CA
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11-19-2019 01:29 PM
What version and patch is installed?

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11-19-2019 02:05 PM
Version 2.4.0.357 patch 6
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11-20-2019 01:50 AM
Hi @Richard Lucht ,
Can you please try to rebuild the internal CA on the ISE and see if this resolves the issue?
Regenerate Internal CA of the ISE: Administration > System > Certificates > Certificate Signing Request > Generate CSR > ISE Root CA
Please 'RATE' and 'MARK ACCEPTED', if applicable.
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06-17-2023 07:18 PM
After weeks of struggling with this issue.
I ended up generating a new Root CA and DNAc could join successfully. At some point I blamed a bug. Running ISE 3.1 and DNA Version 2.2.3.6.
I could have broken the certchains on ISE when doing an upgrade and when I recovered admin password.
Checked my radius clients,, they were not affected by regeneration of new Root CA.
