Can you please post the Intel reference; I don't think that Cisco is deviating from any Intel specifications.
B200-M4 uses
Registered ECC DDR4 DIMMs (RDIMMs) or load-reduced ECC DDR4 DIMMs (LRDIMMs)
The frequency of DDR4 LRDIMMs remains the same whether it is used in 1 DPC or 2 DPC configurations.