Hello,
Is ir CATOS or IOS? Can you please send current config and "show ver", "show flash:", "show boot".
Possibilities can be
Your boot record might be corrupted or not correct so please start checking with that. You may need to remove old and re-add new one.
You may not have enough privileges to change conf reg in conf t mode (just one of the guesses). You may send the exact message you get doing that to check further in more detail.
You can try changing that in ROMMON once the switch reloaded from ROMMON using set commands and changing confreg to 0x2102.
But would be easier to check if you can send those commands.
Nik
HTH,
Niko