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Will there be a draw back to enable these settings.
There can be a draw back as it can create a head-of-line blocking situation at the port and/or additional latency.
The advantage can be, less dropped packets.
With lots of traffic supporting real-time and/or interactive usage, it's often better to leave these settings off.
The foregoing assumes "stock" Ethernet.
For various network vendors viewpoints, see: http://www.networkworld.com/netresources/0913flow2.html
