Hey jackson.norman. l@dol.gov
Make sure that all PSN certs are installed on the Azure side and that all relevant ACLs are in place allowing communication to and from Azure Intune. Also, not sure if this is version specific or not but, if there is a "reply URL" section, make sure the PSNs are configure there as well.
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AnyConnect Compatibility with Microsoft Windows 10
AnyConnect 4.1MR4(4.1.04011) and later are compatible with Windows 10 official release. Technical Assistance Center (TAC) support is available beginning on 7/29/2015.
For best results, we recommend a clean install of AnyConnect on a Windows 10 system and not an upgrade from Windows 7/8/8.1. If you are planning to perform an upgrade from Windows 7/8/8.1 with AnyConnect pre-installed, make sure that you first upgrade AnyConnect prior to uprading the operating system. The Network Access Manager Module must be uninstalled prior to upgrading to Windows 10. After the system upgrade is complete, you can re-install Network Access Manager on the system. You may also choose to fully uninstall AnyConnect and re-install one of the supported versions after upgrading to Windows 10.
This is taken from AC 4.6 Release notes here: https://www.cisco.com/c/en/us/td/docs/security/vpn_client/anyconnect/anyconnect46/release/notes/b_Release_Notes_AnyConnect_4_6.html#reference_A63E6B4B06D949CAB56BB24EF9B28F4A
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